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Short for "hexadecimal numbering system": a numbering system which uses a base of 16. The first ten digits are 0-9 and the next six are A-F.Machine language programs are often written in hexadecimal notation. The hex number system is very useful in cases where computer words are composed of multiples of 4 bits (that is, 4-bit words, 8-bit words, 16- bit words, and so on).When a number is written in base 16, it is preceded by a dollar sign ("$"). For example, $F3 is the hexadecimal representation for the decimal number 243.