ZENworks 11 SP2 and higher now supports an option to Disable support for dynamic groups. All prior versions of ZENworks always attempt to locate the user’s membership in dynamic groups. Locating a user's membership in dynamic groups is an intensive LDAP query; disabling the support for dynamic groups will reduce the LDAP overhead.
To ignore dynamic groups, select Yes to Ignore Dynamic Groups in eDirectory inside that user source's configuration section of the ZCC.