We often have to deal with GroupWise performance questions, in fact my visit to Hong Kong at the beginning of this month was one such issue. In the vast majority of cases the problem turns out to be disk or SAN related, and Hong Kong was no exception (their SAN vendor tested their disks running at 108% capacity!).
So, any amount of tuning is not going to help, however, one of the suggestions we make is to set a whole pile of SET parameters on the NetWare servers. A good resource for this is the GWTUNE.NCF from one of our forum sysops which suggests parameters and values based on years of combined GroupWise and NetWare experience.
My question to you all out there is how many of you have used this file to tune your GW servers and what magnitude of improvement have you seen? Are there any other settings that you use that you have seen make a difference?