GroupWise Mobility Service 2014 R2 allows the Microsoft Outlook 2013 and 2016 clients for Windows and the Microsoft Outlook app to run against a GroupWise backend via Microsoft ActiveSync 14.1 protocol.
Section 8.1, Configuring GroupWise Mobility Service to Support Microsoft Outlook Clients
Section 8.2, Setting Up Microsoft Outlook Clients
Section 8.3, Known Limitations